Pizza cooked at high temperatures (400°F+) effectively kills listeria and other bacteria that may be present in pepperoni. The key is ensuring the pizza is freshly baked and served hot, not lukewarm.
A "Generally Safe" rating means this food doesn’t carry a pregnancy-specific safety concern beyond ordinary food-handling practices — the same basic hygiene and storage habits that apply to anyone. These ratings are based on general guidance from the FDA, ACOG, CDC, and USDA rather than a claim that every possible preparation of the food is automatically fine; how something is prepared, stored, and served still matters. If a "generally safe" food has any handling caveats (like a preparation method or freshness window), they’re noted separately in the sections below rather than changing the overall rating.